A new study by Chinese scientists shows that men’s mortality from COVID-19 2.4 times higher than in women, and the disease takes them in a more severe form. The results were published in the journal Frontiers in Public Health.
Novel coronavirus infection COVID-19 remains largely a mystery to scientists. In particular, they don’t yet fully understand why the disease for some is a deadly danger, while the other proceeds in an asymptomatic form.
Almost from the beginning of the pandemic, it was clear that the main risk group includes the elderly and people with underlying medical conditions such as diabetes, cardiovascular diseases and respiratory diseases. Much has been written about the features COVID-19 in children who have this disease usually occurs in a milder form.
Chinese medical researchers from the Beijing hospital Tongren performed the first analysis of gender differences in morbidity and mortality from COVID-19. The results of the study showed that men and women are equally susceptible to infection with the virus, but men are significantly more likely to suffer from severe consequences of the disease and die.
“In early January we noticed that the number of men dying from COVID-19 was higher than women — presented in a press release publishing the words of head of research, Dr. Jin-kui Jana (Jin-Kui Yang). — Discovering that no one has assessed gender differences in patients with COVID-19, we began the study”.
In the analysis were included 43 patients, which doctors treated yourself, and 1056 patients with COVID-19 from a public database. Given that the new coronavirus SARS-CoV-2-like virus is behind the outbreak of acute respiratory syndrome SARS in 2003, he also uses ACE2 protein to penetrate the cell, scientists have added a sample data for 524 patients with SARS in 2003. Age and the number of infected men and women in the sample were the same.
The authors ‘ conclusions confirm that among patients with COVID-19 the group with the most severe symptoms and highest risk of death are elderly people with concomitant diseases. But among the remaining men, as a rule, the disease was more severe than in women.
In the overall dataset COVID-19 more than 70 percent of the dead patients were men, and this means that men have a mortality rate almost 2.5 times higher than in women, regardless of age. The data set for SARS 2003 the researchers found a similar trend.
Interestingly, the levels of ACE2 protein involved in a virus attack, as in SARS, and COVID-19, was highest in patients with cardiovascular disease and diabetes as well as in all men, regardless of age. Perhaps, in the opinion of the authors that this is the reason that the virus attacks the men stronger.
According to scientists, to determine exactly why men COVID-19 is more severe and mortality is higher, need additional, more extensive research. However, the results obtained is the first visual proof of the greater vulnerability of men from the new coronavirus that will better denote the group of maximum risk.
“We recommend that elderly male patients have been for more supportive care and immediate access to intensive care,” — said Dr. Yang.