The U.S. could double its COVID-19 vaccine availability overnight. What’s the holdup?

What if we could instantly double COVID-19 vaccine availability in America?

This is the tantalizing prospect raised by data collected while testing the double-dose regimen for the Moderna and Pfizer vaccines. As two Canadian researchers highlighted in a letter to the New England Journal of Medicine this month, both vaccines have been found to achieve 92 percent efficacy 14 days after a recipient has been given just one dose. The second dose, administered three to four weeks after the first, offers comparatively small gains by this measure: It boosts the Pfizer vaccine’s efficacy to 95 percent, and the Moderna vaccine’s to 94 percent, differences of just three and two points, respectively.


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